End-stage renal disease with dialysisImage

End-stage renal disease with dialysis

Medical Description

The end result of many renal diseases, End-Stage Renal Disease (ESRD) is a complete or near complete failure of the kidneys to function to excrete wastes, concentrate urine, and regulate electrolytes.

This condition is associated with chronic renal failure. The kidneys of a patient with ESRD show continually increasing levels of blood urea nitrogen (BUN) and serum creatinine, toxic substances that would be execreted in the urine of a healthy patient. Chronic renal failure can be treated by dialysis or by kidney transplantation.

ESRD is sometimes called chronic kidney failure or Stage 5 Renal Failure. Stage 5 refers to the final stage of decline in kidney GFR, or kidney glomerular filtration rate, as defined by the National Kidney Foundation.

Sources: “End Stage Renal Disease,” Intellihealth.Com, November 5, 2007; Mauro Verrelli, MD, FRCPC, FACP, “Chronic Renal Failure,” eMedicine, June 7, 2006, retrieved November 8, 2007.


Symptoms

  • Abdominal pain;
  • Back pain;
  • Decreased urination, no urine output, or conversely, high urine output;
  • Detectable abdominal mass;
  • Diarrhea, or bloody diarrhea;
  • Difficulty breathing;
  • exposure to heavy metals or toxic solvents
  • Fatigue;
  • Fever;
  • Headache;
  • Hemorrhage;
  • Hiccups;
  • History of recent infection;
  • History of trauma ;
  • Inflammation of the covering of the heart;
  • inflammation of the eye;
  • Itching;
  • Muscle cramps;
  • Nausea;
  • Nosebleeds;
  • Pale skin;
  • Poor appetite;
  • Rash;
  • Seizures;
  • Severe vomiting;
  • Swelling of the tissues;
  • Weakness; and
  • Weight loss.

General Information

End-stage Renal Disease (ESRD) is a condition in which the kidneys cease to function as normal. Typically, ESRD is diagnosed when the kidneys are functioning at less than 15% of their normal capacity and will fail, causing the death of the patient, sometimes within weeks, if a kidney transplant donor is not found. At this point, a mechanical process called dialysis is used to do the kidney’s work, or a kidney transplant is required to prevent major complications, including death.

ESRD can be caused by high blood pressure, vascular disease, rheumatic or autoimmune diseases, genetic disorders, or exposure to toxic drugs, such as contrast dyes and certain antibiotics.

A study reported January 25, 2006, in the New England Journal of Medicine shows that Trasylol linked to serious, life-threatening side effects. Trasylol, known generically as Aprotinin, is manufactured by Bayer AG and is administered by injection during coronary artery bypass graft (CABG) surgery (commonly known as cardiac bypass surgery) and other surgeries to induce clotting in the blood, preventing hemorrhaging. The study of 4,374 patients demonstrated that Trasylol at least doubles the risk of kidney failure.

The study estimated that as many as 10,000 patients may now be on dialysis due to kidney failure after heart surgery where they were administered Trasylol.

Sales of the clotting drug Trasylol have been suspended by its manufacturer amid studies suggesting its risks may outweigh its benefits. Most patients are unaware they were administered Trasylol during their heart surgery or other surgery.

Sources: “End Stage Renal Disease,” Intellihealth.Com, November 5, 2007; Mauro Verrelli, MD, FRCPC, FACP, “Chronic Renal Failure,” eMedicine, June 7, 2006, retrieved November 8, 2007; Richard Dingwall, et.al, Royal Infirmary of Edinburgh, “End stage renal failure and its treatment,” renux.dmed.ed.ac.uk/EdREN, July 25, 2006, retrieved November 8, 2007; Thomas H. Maugh II, “Multiple Risks of Surgery Drug Seen,” Los Angeles Times, January 26, 2006..


Did you develop chronic kidney failure which led to dialysis after undergoing a surgical procedure?

If you or a loved one underwent coronary artery bypass graft (CABG) or other heart surgery, an orthopedic or other procedure, and were later forced onto dialysis due to chronic kidney failure; or if a loved one died from End-Stage Renal Disease (ESRD) after having heart surgery, an investigation into the larger issues of your case may be beneficial to you and your family.


Clotting drug used during some surgeries linked to ESRD

Clotting drug used during some surgeries linked to ESRD

Trasylol, known generically as Aprotinin, is manufactured by Bayer AG and is administered by injection during coronary artery bypass graft (CABG) surgery (commonly known as cardiac bypass surgery) and other surgeries to induce clotting in the blood, preventing hemorrhaging.

A study reported January 25, 2006, in the New England Journal of Medicine shows that Trasylol is linked to serious, life-threatening side effects. The study of 4,374 patients demonstrated that Trasylol at least doubles the risk of * kidney failure* . The study estimated that as many as 10,000 patients may now be on dialysis due to * kidney failure* after * heart surgery* where they were administered Trasylol .

Source: Thomas H. Maugh II, “Multiple Risks of Surgery Drug Seen,” Los Angeles Times, January 26, 2006.


Do you need a Product Liability Lawyer for your End-Stage Renal Disease Case? – Free Call, No Obligation

If you or someone you love is suffering from End-Stage Renal Disease, you are no doubt aware that many people with ESRD die from the disease, sometimes waiting for a kidney transplant. Many others die from organ rejection.

However, you should also be aware that sales of the clotting drug Trasylol have been suspended by its manufacturer amid studies suggesting its risks may outweigh its benefits. Most patients will not know they were administered Trasylol during their heart surgery or other surgery.

Contact our personal injury law firm today. A consultation with a product liability lawyer may be in your best interest. If Bayer AG knew the risks of taking Trayslol were more dangerous than it claimed, you may be entitled to compensation for the injuries you may have suffered as a result.

Our personal injury law firm may be able to investigate the circumstances of your case. Your information will be reviewed by a lawyer who may be able to help you gain compensation from an ESRD lawsuit.


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