Parnate

tranylcypromine sulfate

Parnate is a monoamine oxidase inhibitor (MAOI)for the treatment of major depressive disorders and anxiety disorders. Parnate is intended for depressed patients who have not been helped by other medications.

The drug works by increasing the concentrations of the neurotransmitters norepinephrine, epinephrine, and serotonin.

Common side effects observed in patients using Parnate are:

• drowsiness
• weakness
• dry mouth
• loss of appetite
• diarrhea
• constipation
• stomach pain
• blurred vision
• chills
• ringing in the ears
• muscle tightening or jerking
• uncontrollable shaking of any part of the body
• numbness, burning, or tingling in the arms or legs
• difficulty urinating
• decreased sexual ability
• hair loss
• rash

Although rare, patients experiencing any of the following serious side effects should immediately contact their doctors:

• headache
• slow, fast, or pounding heartbeat
• chest pain or tightness
• tightening of the throat
• nausea
• sweating
• fever
• cold, clammy skin
• dizziness
• neck stiffness or soreness
• sensitivity to light
• widened pupils (black circles in the middle of the eyes)
• swelling of arms, hands, feet, ankles, or lower legs
• unusual bleeding or bruising
• pain in the upper right part of the stomach
• flu-like symptoms
• yellowing of the skin or eyes

Source: “Tranylcypromine,” MedlinePlus Drug Information Sheet, July 1, 2006.