Dilantin
phenytoin sodium
Dilantin, generically known as phenytoin sodium, is an antiepileptic drug used to prevent seizures. The drug slows down impulses in the brain that can cause seizures.
In a recent article in Metroactive by Loren Stein, entitled “Without Warning,” the drug was singled out as a possible cause of Steven-Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN). Both are potentially fatal diseases that cause severe, systematic blistering and burning of the skin.
Additionally, eMedicine’s online post on Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) suggests this drug as a possible cause of the diseases. SJS and TEN are potentially fatal diseases in children that cause severe, systematic blistering and burning of the skin.
Some of the drugs most serious side effects include:
- swollen glands
- fever, sore throat, and headache with a severe blistering, peeling, and red skin rash
- confusion, hallucinations, unusual thoughts or behavior
- slurred speech, loss of balance or coordination
- restless muscle movements in your eyes, tongue, jaw, or neck
- tremor (uncontrolled shaking)
- extreme thirst or hunger, urinating more than usual
- nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes)
- easy bruising or bleeding
- swollen or tender gums
- changes in the shape of your face or lips
- mild skin rash or itching
- dizziness, nervousness, sleep problems (insomnia)
- twitching
- nausea, vomiting, constipation;
- headache or
- joint pain.


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